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Plasma-based early screening and monitoring of EGFR mutations in NSCLC patients by a 3-color digital PCR assay
BACKGROUND: Noninvasive plasma-based detection of EGFR mutations using digital PCR promises a fast, sensitive and reliable approach to predicting the efficiency of EGFR-TKI. However, the low throughput and high cost of digital PCR restricts its clinical application. METHODS: We designed a digital PC...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592053/ https://www.ncbi.nlm.nih.gov/pubmed/32782293 http://dx.doi.org/10.1038/s41416-020-1024-2 |