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Subcellular Localization of MxB Determines Its Antiviral Potential against Influenza A Virus

Mx proteins are interferon (IFN) type I (α/β)- and type III (λ)-induced effector proteins with intrinsic antiviral activity. Mammalian Mx proteins show different subcellular localizations and distinct yet partially overlapping viral specificities. However, the precise mechanism(s) of antiviral actio...

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Detalles Bibliográficos
Autores principales: Steiner, Fiona, Pavlovic, Jovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592211/
https://www.ncbi.nlm.nih.gov/pubmed/32907985
http://dx.doi.org/10.1128/JVI.00125-20