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Respiratory Syncytial Virus Sequesters NF-κB Subunit p65 to Cytoplasmic Inclusion Bodies To Inhibit Innate Immune Signaling

Viruses routinely employ strategies to prevent the activation of innate immune signaling in infected cells. Respiratory syncytial virus (RSV) is no exception, as it encodes two accessory proteins (NS1 and NS2) which are well established to block interferon signaling. However, RSV-encoded mechanisms...

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Detalles Bibliográficos
Autores principales: Jobe, Fatoumatta, Simpson, Jennifer, Hawes, Philippa, Guzman, Efrain, Bailey, Dalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592213/
https://www.ncbi.nlm.nih.gov/pubmed/32878896
http://dx.doi.org/10.1128/JVI.01380-20