Disruption of Adaptive Immunity Enhances Disease in SARS-CoV-2-Infected Syrian Hamsters

Animal models recapitulating human COVID-19 disease, especially severe disease, are urgently needed to understand pathogenesis and to evaluate candidate vaccines and therapeutics. Here, we develop novel severe-disease animal models for COVID-19 involving disruption of adaptive immunity in Syrian ham...

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Detalles Bibliográficos
Autores principales: Brocato, Rebecca L., Principe, Lucia M., Kim, Robert K., Zeng, Xiankun, Williams, Janice A., Liu, Yanan, Li, Rong, Smith, Jeffrey M., Golden, Joseph W., Gangemi, Dave, Youssef, Sawsan, Wang, Zhongde, Glanville, Jacob, Hooper, Jay W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592214/
https://www.ncbi.nlm.nih.gov/pubmed/32900822
http://dx.doi.org/10.1128/JVI.01683-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592214/
https://www.ncbi.nlm.nih.gov/pubmed/32900822
http://dx.doi.org/10.1128/JVI.01683-20

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