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Lysophosphatidic acid-RAGE axis promotes lung and mammary oncogenesis via protein kinase B and regulating tumor microenvironment

BACKGROUND: Receptor for advanced glycation end products (RAGE) is a multi-ligand transmembrane receptor of the immunoglobulin superfamily. Lysophosphatidic acid (LPA) is a ligand for RAGE and is involved in physiological and pathophysiological conditions including cancer. However, RAGE-LPA axis is...

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Detalles Bibliográficos
Autores principales: Ray, Rashmi, Jangde, Nitish, Singh, Satyendra Kumar, Sinha, Sunita, Rai, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592382/
https://www.ncbi.nlm.nih.gov/pubmed/33109194
http://dx.doi.org/10.1186/s12964-020-00666-y