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CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes

IL-22 is a member of the IL-10 cytokine family involved in host protection against extracellular pathogens, by promoting epithelial cell regeneration and barrier functions. Dysregulation of IL-22 production has also frequently been observed in acute respiratory distress syndrome (ARDS) and several c...

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Detalles Bibliográficos
Autores principales: Kunkl, Martina, Amormino, Carola, Frascolla, Simone, Sambucci, Manolo, De Bardi, Marco, Caristi, Silvana, Arcieri, Stefano, Battistini, Luca, Tuosto, Loretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592429/
https://www.ncbi.nlm.nih.gov/pubmed/33178223
http://dx.doi.org/10.3389/fimmu.2020.590964