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CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes
IL-22 is a member of the IL-10 cytokine family involved in host protection against extracellular pathogens, by promoting epithelial cell regeneration and barrier functions. Dysregulation of IL-22 production has also frequently been observed in acute respiratory distress syndrome (ARDS) and several c...
Autores principales: | Kunkl, Martina, Amormino, Carola, Frascolla, Simone, Sambucci, Manolo, De Bardi, Marco, Caristi, Silvana, Arcieri, Stefano, Battistini, Luca, Tuosto, Loretta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592429/ https://www.ncbi.nlm.nih.gov/pubmed/33178223 http://dx.doi.org/10.3389/fimmu.2020.590964 |
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