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Transcellular Model for Neutral and Charged Nanoparticles Across an In Vitro Blood–Brain Barrier

PURPOSE: The therapeutic drug-loaded nanoparticles (NPs, 20–100 nm) have been widely used to treat brain disorders. To improve systemic brain delivery efficacy of these NPs, it is necessary to quantify their transport parameters across the blood–brain barrier (BBB) and understand the underlying tran...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Fan, Jie, Li, Guanglei, Yin, Zhaokai, Fu, Bingmei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592456/
https://www.ncbi.nlm.nih.gov/pubmed/33113565
http://dx.doi.org/10.1007/s13239-020-00496-6