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NF-κB maintains the stemness of colon cancer cells by downregulating miR-195-5p/497–5p and upregulating MCM2

BACKGROUND: Colon cancer represents one of the leading causes of gastrointestinal tumors in industrialized countries, and its incidence appears to be increasing at an alarming rate. Accumulating evidence has unveiled the contributory roles of cancer stem cells (CSCs) in tumorigenicity, recurrence, a...

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Detalles Bibliográficos
Autores principales: Wang, Longgang, Guo, Jinxiang, Zhou, Jin, Wang, Dongyang, Kang, Xiuwen, Zhou, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592593/
https://www.ncbi.nlm.nih.gov/pubmed/33109220
http://dx.doi.org/10.1186/s13046-020-01704-w