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Threonyl-tRNA Synthetase Promotes T Helper Type 1 Cell Responses by Inducing Dendritic Cell Maturation and IL-12 Production via an NF-κB Pathway

Threonyl-tRNA synthetase (TRS) is an aminoacyl-tRNA synthetase that catalyzes the aminoacylation of tRNA by transferring threonine. In addition to an essential role in translation, TRS was extracellularly detected in autoimmune diseases and also exhibited pro-angiogenetic activity. TRS is reported t...

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Detalles Bibliográficos
Autores principales: Jung, Hak-Jun, Park, Su-Ho, Cho, Kyung-Min, Jung, Kwang Il, Cho, Daeho, Kim, Tae Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592646/
https://www.ncbi.nlm.nih.gov/pubmed/33178197
http://dx.doi.org/10.3389/fimmu.2020.571959