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Computational Modeling of Catecholamines Dysfunction in Alzheimer’s Disease at Pre-Plaque Stage

BACKGROUND: Alzheimer’s disease (AD) etiopathogenesis remains partially unexplained. The main conceptual framework used to study AD is the Amyloid Cascade Hypothesis, although the failure of recent clinical experimentation seems to reduce its potential in AD research. OBJECTIVE: A possible explanati...

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Detalles Bibliográficos
Autores principales: Caligiore, Daniele, Silvetti, Massimo, D’Amelio, Marcello, Puglisi-Allegra, Stefano, Baldassarre, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592658/
https://www.ncbi.nlm.nih.gov/pubmed/32741822
http://dx.doi.org/10.3233/JAD-200276