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Computational Modeling of Catecholamines Dysfunction in Alzheimer’s Disease at Pre-Plaque Stage
BACKGROUND: Alzheimer’s disease (AD) etiopathogenesis remains partially unexplained. The main conceptual framework used to study AD is the Amyloid Cascade Hypothesis, although the failure of recent clinical experimentation seems to reduce its potential in AD research. OBJECTIVE: A possible explanati...
Autores principales: | Caligiore, Daniele, Silvetti, Massimo, D’Amelio, Marcello, Puglisi-Allegra, Stefano, Baldassarre, Gianluca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592658/ https://www.ncbi.nlm.nih.gov/pubmed/32741822 http://dx.doi.org/10.3233/JAD-200276 |
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