Amyloidogenic Nanoplaques in Cerebrospinal Fluid: Relationship to Amyloid Brain Uptake and Clinical Alzheimer’s Disease in a Memory Clinic Cohort

BACKGROUND: Aggregation of amyloid-β (Aβ) is an early pathological event in Alzheimer’s disease (AD). Consequently, measures of pathogenic aggregated Aβ are attractive biomarkers for AD. Here, we use a recently developed Thioflavin-T-Fluorescence Correlation Spectroscopy (ThT-FCS) assay to quantify...

Descripción completa

Detalles Bibliográficos
Autores principales: Aksnes, Mari, Müller, Ebba Glersen, Tiiman, Ann, Edwin, Trine Holt, Terenius, Lars, Revheim, Mona-Elisabeth, Vukojević, Vladana, Bogdanović, Nenad, Knapskog, Anne-Brita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592690/
https://www.ncbi.nlm.nih.gov/pubmed/32741818
http://dx.doi.org/10.3233/JAD-200237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592690/
https://www.ncbi.nlm.nih.gov/pubmed/32741818
http://dx.doi.org/10.3233/JAD-200237

Ejemplares similares