Loss of p120ctn causes EGFR-targeted therapy resistance and failure

Epidermal growth factor receptor (EGFR) plays a vital role in cell division and survival signaling pathways. EGFR is activated in nearly every cancer type, and its high expression in tumors is correlated with poor patient outcome. Altogether, EGFR is a prime candidate as a therapeutic target. While...

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Detalles Bibliográficos
Autores principales: Landmesser, Mary E., Raup-Konsavage, Wesley M., Lehman, Heather L., Stairs, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592761/
https://www.ncbi.nlm.nih.gov/pubmed/33112928
http://dx.doi.org/10.1371/journal.pone.0241299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592761/
https://www.ncbi.nlm.nih.gov/pubmed/33112928
http://dx.doi.org/10.1371/journal.pone.0241299

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