Anemarsaponin BII inhibits the activity of CYP3A4, 2D6, and 2E1 with human liver microsomes

CONTEXT: Anemarsaponin BII is one of the most active saponins isolated from Anemarrhena asphodeloides Bunge (Asparagaceae), a commonly used Chinese traditional paediatric medicine. OBJECTIVE: This study investigates the effects of anemarsaponin BII on the activity of CYP450s to provide more guidance...

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Detalles Bibliográficos
Autores principales: Wang, Mingwei, Jiang, Wei, Zhou, Juan, Xue, Xiujuan, Yin, Changlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592892/
https://www.ncbi.nlm.nih.gov/pubmed/33103940
http://dx.doi.org/10.1080/13880209.2020.1835996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592892/
https://www.ncbi.nlm.nih.gov/pubmed/33103940
http://dx.doi.org/10.1080/13880209.2020.1835996

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