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PE homeostasis rebalanced through mitochondria-ER lipid exchange prevents retinal degeneration in Drosophila
The major glycerophospholipid phosphatidylethanolamine (PE) in the nervous system is essential for neural development and function. There are two major PE synthesis pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum (ER) and the phosphatidylserine decarboxylase (PSD) pathway in mito...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592913/ https://www.ncbi.nlm.nih.gov/pubmed/33064773 http://dx.doi.org/10.1371/journal.pgen.1009070 |