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Gate-keeper of ion transport—a highly conserved helix-3 tryptophan in a channelrhodopsin chimera, C1C2/ChRWR

Microbial rhodopsin is a large family of membrane proteins having seven transmembrane helices (TM1-7) with an all-trans retinal (ATR) chromophore that is covalently bound to Lys in the TM7. The Trp residue in the middle of TM3, which is homologous to W86 of bacteriorhodopsin (BR), is highly conserve...

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Detalles Bibliográficos
Autores principales: Nagasaka, Yujiro, Hososhima, Shoko, Kubo, Naoko, Nagata, Takashi, Kandori, Hideki, Inoue, Keiichi, Yawo, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593130/
https://www.ncbi.nlm.nih.gov/pubmed/33173715
http://dx.doi.org/10.2142/biophysico.BSJ-2020007