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High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo

OBJECTIVE: Maternal embryonic leucine zipper kinase (MELK) is receiving an attention as a therapeutic target in various types of cancers. In this study, we aimed to evaluate the prognostic significance of MELK expression in ovarian cancer using clinical samples, and assessed the efficacy of a small...

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Detalles Bibliográficos
Autores principales: Ikeda, Yuji, Sato, Sho, Yabuno, Akira, Shintani, Daisuke, Ogasawara, Aiko, Miwa, Maiko, Zewde, Makda, Miyamoto, Takashi, Fujiwara, Keiichi, Nakamura, Yusuke, Hasegawa, Kosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593222/
https://www.ncbi.nlm.nih.gov/pubmed/33078598
http://dx.doi.org/10.3802/jgo.2020.31.e93