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Long-Term Consequences of High Titer Neutralizing Antibodies to Interferon-β in Multiple Sclerosis

BACKGROUND: Neutralizing anti-drug antibodies (NAbs) to interferon beta (IFNβ) develop in up to 47% of multiple sclerosis (MS) treated patients inhibiting treatment effect of IFNβ. However, the long-term effect of NAbs remain unknown. OBJECTIVE: To investigate the long-term consequences of high tite...

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Detalles Bibliográficos
Autores principales: Dunn, Nicky, Fogdell-Hahn, Anna, Hillert, Jan, Spelman, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593513/
https://www.ncbi.nlm.nih.gov/pubmed/33178215
http://dx.doi.org/10.3389/fimmu.2020.583560