Restoration of ceramide de novo synthesis by the synthetic retinoid ST1926 as it induces adult T-cell leukemia cell death

Ceramide (Cer) is a bioactive cellular lipid with compartmentalized and tightly regulated levels. Distinct metabolic pathways lead to the generation of Cer species with distinguishable roles in oncogenesis. Deregulation of Cer pathways has emerged as an important mechanism for acquired chemotherapeu...

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Detalles Bibliográficos
Autores principales: Ghandour, Botheina, Pisano, Claudio, Darwiche, Nadine, Dbaibo, Ghassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593536/
https://www.ncbi.nlm.nih.gov/pubmed/33048123
http://dx.doi.org/10.1042/BSR20200050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593536/
https://www.ncbi.nlm.nih.gov/pubmed/33048123
http://dx.doi.org/10.1042/BSR20200050

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