Generating Multibillion Chemical Space of Readily Accessible Screening Compounds

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An approach to the generation of ultra-large chemical libraries of readily accessible (“REAL”) compounds is described. The strategy is based on the use of two- or three-step three-component reaction sequences and available starting materials with pre-validated chemical reactivity. After the prelimin...

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Detalles Bibliográficos
Autores principales: Grygorenko, Oleksandr O., Radchenko, Dmytro S., Dziuba, Igor, Chuprina, Alexander, Gubina, Kateryna E., Moroz, Yurii S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593547/
https://www.ncbi.nlm.nih.gov/pubmed/33145486
http://dx.doi.org/10.1016/j.isci.2020.101681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593547/
https://www.ncbi.nlm.nih.gov/pubmed/33145486
http://dx.doi.org/10.1016/j.isci.2020.101681

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