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Generating Multibillion Chemical Space of Readily Accessible Screening Compounds

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An approach to the generation of ultra-large chemical libraries of readily accessible (“REAL”) compounds is described. The strategy is based on the use of two- or three-step three-component reaction sequences and available starting materials with pre-validated chemical reactivity. After the prelimin...

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Detalles Bibliográficos
Autores principales:	Grygorenko, Oleksandr O., Radchenko, Dmytro S., Dziuba, Igor, Chuprina, Alexander, Gubina, Kateryna E., Moroz, Yurii S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593547/ https://www.ncbi.nlm.nih.gov/pubmed/33145486 http://dx.doi.org/10.1016/j.isci.2020.101681

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