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Exosomal PD-L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies

As a classical immune checkpoint molecule, PD-L1 on the surface of tumor cells plays a pivotal role in tumor immunosuppression, primarily by inhibiting the antitumor activities of T cells by binding to its receptor PD-1. PD-1/PD-L1 inhibitors have demonstrated unprecedented promise in treating vario...

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Detalles Bibliográficos
Autores principales: Zhou, Kaijian, Guo, Shu, Li, Fei, Sun, Qiang, Liang, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593554/
https://www.ncbi.nlm.nih.gov/pubmed/33178688
http://dx.doi.org/10.3389/fcell.2020.569219