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Analytical and Clinical Validation for RT-qPCR Detection of SARS-CoV-2 Without RNA Extraction

Background: The recent COVID-19 pandemic has posed an unprecedented challenge to laboratory diagnosis, based on the amplification of SARS-CoV-2 RNA. With global contagion figures exceeding 4 million persons, the shortage of reagents for RNA extraction represents a bottleneck for testing globally. We...

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Detalles Bibliográficos
Autores principales: Miranda, José P., Osorio, Javiera, Videla, Mauricio, Angel, Gladys, Camponovo, Rossana, Henríquez-Henríquez, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593567/
https://www.ncbi.nlm.nih.gov/pubmed/33178714
http://dx.doi.org/10.3389/fmed.2020.567572