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Lost and Found: Re-searching and Re-scoring Proteomics Data Aids Genome Annotation and Improves Proteome Coverage

Prokaryotic genome annotation is heavily dependent on automated gene annotation pipelines that are prone to propagate errors and underestimate genome complexity. We describe an optimized proteogenomic workflow that uses ribosome profiling (ribo-seq) and proteomic data for Salmonella enterica serovar...

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Detalles Bibliográficos
Autores principales: Willems, Patrick, Fijalkowski, Igor, Van Damme, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593589/
https://www.ncbi.nlm.nih.gov/pubmed/33109751
http://dx.doi.org/10.1128/mSystems.00833-20