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Amino Acid Starvation Sensitizes Resistant Breast Cancer to Doxorubicin-Induced Cell Death

Many clinical trials are beginning to assess the effectiveness of compounds known to regulate autophagy in patients receiving anti-cancer chemotherapy. However, autophagy inhibition, through exogenous inhibitors, or activation, through starvation, has revealed conflicting roles in cancer management...

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Detalles Bibliográficos
Autores principales: Thomas, Mark, Davis, Tanja, Nell, Theo, Sishi, Balindiwe, Engelbrecht, Anna-Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593593/
https://www.ncbi.nlm.nih.gov/pubmed/33178685
http://dx.doi.org/10.3389/fcell.2020.565915