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Transcriptional activation of the mouse Scd2 gene by interdependent enhancers and long noncoding RNAs in ovarian granulosa cells

Specific gene expression in granulosa cells is key for the function of ovary, but the molecular mechanism of transcriptional activation is not well studied. Here we investigated the regulatory mechanism of the mouse stearoyl-CoA desaturase 2 (Scd2) gene encoding an enzyme for lipid metabolism. North...

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Detalles Bibliográficos
Autores principales: MAYAMA, Shota, HAMAZAKI, Nobuhiko, MARUYAMA, Yuki, MATSUBARA, Shin, KIMURA, Atsushi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593631/
https://www.ncbi.nlm.nih.gov/pubmed/32507774
http://dx.doi.org/10.1262/jrd.2019-161