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Littermate-Controlled Experiments Reveal Eosinophils Are Not Essential for Maintaining Steady-State IgA and Demonstrate the Influence of Rearing Conditions on Antibody Phenotypes in Eosinophil-Deficient Mice

Conflicting data has emerged regarding a role for eosinophils in IgA production, with some reports that eosinophils support both secretory and circulating IgA levels during homeostasis. Previous studies have compared antibody levels between wildtype and eosinophil-deficient mice, but these mice were...

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Detalles Bibliográficos
Autores principales: FitzPatrick, Rachael D., Kennedy, Mia H. E., Lawrence, Katherine M., Gauthier, Courtney M., Moeller, Brandon E., Robinson, Andrew N., Reynolds, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593696/
https://www.ncbi.nlm.nih.gov/pubmed/33178185
http://dx.doi.org/10.3389/fimmu.2020.557960