Rational Drug Design for Pseudomonas aeruginosa PqsA Enzyme: An in silico Guided Study to Block Biofilm Formation

Pseudomonas aeruginosa is an opportunistic gram-negative bacterium implicated in acute and chronic nosocomial infections and a leading cause of patient mortality. Such infections occur owing to biofilm formation that confers multidrug resistance and enhanced pathogenesis to the bacterium. In this st...

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Detalles Bibliográficos
Autores principales: Shaker, Bilal, Ahmad, Sajjad, Thai, Thi Duc, Eyun, Seong-il, Na, Dokyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593710/
https://www.ncbi.nlm.nih.gov/pubmed/33195420
http://dx.doi.org/10.3389/fmolb.2020.577316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593710/
https://www.ncbi.nlm.nih.gov/pubmed/33195420
http://dx.doi.org/10.3389/fmolb.2020.577316

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