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Rational Drug Design for Pseudomonas aeruginosa PqsA Enzyme: An in silico Guided Study to Block Biofilm Formation
Pseudomonas aeruginosa is an opportunistic gram-negative bacterium implicated in acute and chronic nosocomial infections and a leading cause of patient mortality. Such infections occur owing to biofilm formation that confers multidrug resistance and enhanced pathogenesis to the bacterium. In this st...
Autores principales: | Shaker, Bilal, Ahmad, Sajjad, Thai, Thi Duc, Eyun, Seong-il, Na, Dokyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593710/ https://www.ncbi.nlm.nih.gov/pubmed/33195420 http://dx.doi.org/10.3389/fmolb.2020.577316 |
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