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Mechanistic Insight on the Interaction between OPN and Integrin ανβ3 in Osteoarthritis

Osteoarthritis (OA) is a joint disease characterized by cartilage degeneration. Osteopontin (OPN) is involved in the initiation, repair, and maintenance of metabolic homeostasis in normal articular cartilage. This study investigated the role of OPN and its interaction with the integrin ανβ3 receptor...

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Detalles Bibliográficos
Autores principales: Yuan, Yuhao, Liu, Qing, Wu, Ziyi, Luo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593734/
https://www.ncbi.nlm.nih.gov/pubmed/33134374
http://dx.doi.org/10.1155/2020/2905634