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Synergistic Effect of MC-LR and C-Terminal Truncated HBx on HepG2 Cells and Their Effects on PP2A Mediated Downstream Target of MAPK Signaling Pathway

C-terminally truncated hepatitis B virus (HBV) X (ctHBx) infection and exposure to microcystins-LR (MC-LR) can lead to human hepatitis and liver cancer, but the mechanism associated with their synergistically effects not been fully elucidated. The ctHBx (HBxΔ4 and HBxΔ32) lentivirus were constructed...

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Detalles Bibliográficos
Autores principales: Xiao, Chanchan, Mei, Fanbiao, Ren, Guanhua, Long, Long, Chen, Maojian, Fang, Xiang, Li, Jilin, Li, Kezhi, Tang, Yanping, Huang, Tianren, Deng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593820/
https://www.ncbi.nlm.nih.gov/pubmed/33193609
http://dx.doi.org/10.3389/fgene.2020.537785