Phase-Separated Transcriptional Condensates Accelerate Target-Search Process Revealed by Live-Cell Single-Molecule Imaging

Compartmentalization by liquid-liquid phase separation is implicated in transcription. It remains unclear whether and how transcriptional condensates accelerate the search of transcriptional regulatory factors for their target sites. Furthermore, the molecular mechanisms by which regulatory factors...

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Detalles Bibliográficos
Autores principales: Kent, Samantha, Brown, Kyle, Yang, Chou-hsun, Alsaihati, Njood, Tian, Christina, Wang, Haobin, Ren, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593837/
https://www.ncbi.nlm.nih.gov/pubmed/33053359
http://dx.doi.org/10.1016/j.celrep.2020.108248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593837/
https://www.ncbi.nlm.nih.gov/pubmed/33053359
http://dx.doi.org/10.1016/j.celrep.2020.108248

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