Deferred Administration of Afobazole Induces Sigma1R-Dependent Restoration of Striatal Dopamine Content in a Mouse Model of Parkinson’s Disease

Previously, we demonstrated that the immediate administration of multitarget anxiolytic afobazole slows down the progression of neuronal damage in a 6-hydroxidodamine (6-OHDA) model of Parkinson’s disease due to the activation of chaperone Sigma1R. The aim of the present study is to evaluate the the...

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Detalles Bibliográficos
Autores principales: Kadnikov, Ilya A., Verbovaya, Ekaterina R., Voronkov, Dmitry N., Voronin, Mikhail V., Seredenin, Sergei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593947/
https://www.ncbi.nlm.nih.gov/pubmed/33076300
http://dx.doi.org/10.3390/ijms21207620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593947/
https://www.ncbi.nlm.nih.gov/pubmed/33076300
http://dx.doi.org/10.3390/ijms21207620

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