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Characterization of Asparagine Deamidation in Immunodominant Myelin Oligodendrocyte Glycoprotein Peptide Potential Immunotherapy for the Treatment of Multiple Sclerosis

Mannan (polysaccharide) conjugated with a myelin oligodendrocyte glycoprotein (MOG) peptide, namely (KG)(5)MOG(35–55), represents a potent and promising new approach for the immunotherapy of Multiple Sclerosis (MS). The MOG(35–55) epitope conjugated with the oxidized form of mannan (poly-mannose) vi...

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Detalles Bibliográficos
Autores principales: Androutsou, Maria-Eleni, Nteli, Agathi, Gkika, Areti, Avloniti, Maria, Dagkonaki, Anastasia, Probert, Lesley, Tselios, Theodore, Golič Grdadolnik, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593956/
https://www.ncbi.nlm.nih.gov/pubmed/33066323
http://dx.doi.org/10.3390/ijms21207566