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Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation

Epstein-Barr virus (EBV) infects 95% of adults worldwide and causes infectious mononucleosis. EBV is associated with endemic Burkitt lymphoma, Hodgkin lymphoma, posttransplant lymphomas, nasopharyngeal and gastric carcinomas. In these cancers and in most infected B-cells, EBV maintains a state of la...

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Detalles Bibliográficos
Autores principales: Zhang, Yuchen, Jiang, Chang, Trudeau, Stephen J., Narita, Yohei, Zhao, Bo, Teng, Mingxiang, Guo, Rui, Gewurz, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593962/
https://www.ncbi.nlm.nih.gov/pubmed/33109754
http://dx.doi.org/10.1128/mBio.01063-20