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Effect of TMAO and Urea on Dimers and Tetramers of Amyloidogenic Heptapeptides ((23)FGAILSS(29))

[Image: see text] Human islet amyloid polypeptide (hIAPP) (1–37) is an intrinsically disordered protein that is released with insulin by β-cells found in the pancreas. Under certain environmental conditions, hIAPP can aggregate, which leads to β-cell death. FGAILSS (23–29) residues of the hIAPP prot...

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Detalles Bibliográficos
Autores principales: Khan, Ashma, Nayeem, Shahid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593999/
https://www.ncbi.nlm.nih.gov/pubmed/33134659
http://dx.doi.org/10.1021/acsomega.0c01031