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Effect of TMAO and Urea on Dimers and Tetramers of Amyloidogenic Heptapeptides ((23)FGAILSS(29))
[Image: see text] Human islet amyloid polypeptide (hIAPP) (1–37) is an intrinsically disordered protein that is released with insulin by β-cells found in the pancreas. Under certain environmental conditions, hIAPP can aggregate, which leads to β-cell death. FGAILSS (23–29) residues of the hIAPP prot...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593999/ https://www.ncbi.nlm.nih.gov/pubmed/33134659 http://dx.doi.org/10.1021/acsomega.0c01031 |