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A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations

High-throughput sequencing such as those provided by Illumina are an efficient way to understand sequence variation within viral populations. However, challenges exist in distinguishing process-introduced error from biological variance, which significantly impacts our ability to identify sub-consens...

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Detalles Bibliográficos
Autores principales:	King, David J., Freimanis, Graham, Lasecka-Dykes, Lidia, Asfor, Amin, Ribeca, Paolo, Waters, Ryan, King, Donald P., Laing, Emma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594041/ https://www.ncbi.nlm.nih.gov/pubmed/33092085 http://dx.doi.org/10.3390/v12101187

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