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Synthesis of Benzimidazole–Based Analogs as Anti Alzheimer’s Disease Compounds and Their Molecular Docking Studies

We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff bases 2 (a–m), and characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase (AchE) and butyrylcholinesterase (BchE) inhibition activities. All the syn...

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Detalles Bibliográficos
Autores principales: Adalat, Bushra, Rahim, Fazal, Taha, Muhammad, Alshamrani, Foziah J., Anouar, El Hassane, Uddin, Nizam, Shah, Syed Adnan Ali, Ali, Zarshad, Zakaria, Zainul Amiruddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594061/
https://www.ncbi.nlm.nih.gov/pubmed/33092223
http://dx.doi.org/10.3390/molecules25204828