Design and Synthesis of Helical N-Terminal l-Prolyl Oligopeptides Possessing Hydrocarbon Stapling

We designed and synthesized helical short oligopeptides with an l-proline on the N-terminus and hydrocarbon stapling on the side chain. Side-chain stapling is a frequently used method for the development of biologically active peptides. Side-chain stapling can stabilize the secondary structures of p...

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Detalles Bibliográficos
Autores principales: Ueda, Atsushi, Higuchi, Mei, Sato, Kazuki, Umeno, Tomohiro, Tanaka, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594088/
https://www.ncbi.nlm.nih.gov/pubmed/33066194
http://dx.doi.org/10.3390/molecules25204667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594088/
https://www.ncbi.nlm.nih.gov/pubmed/33066194
http://dx.doi.org/10.3390/molecules25204667

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