Assessing the Direct Binding of Ark-Like E3 RING Ligases to Ubiquitin and Its Implication on Their Protein Interaction Network

The ubiquitin pathway required for most proteins’ targeted degradation involves three classes of enzymes: E1-activating enzyme, E2-conjugating enzyme, and E3-ligases. The human Ark2C is the single known E3 ligase that adopts an alternative, Ub-dependent mechanism for the activation of Ub transfer in...

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Detalles Bibliográficos
Autores principales: Mintis, Dimitris G., Chasapi, Anastasia, Poulas, Konstantinos, Lagoumintzis, George, Chasapis, Christos T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594095/
https://www.ncbi.nlm.nih.gov/pubmed/33086510
http://dx.doi.org/10.3390/molecules25204787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594095/
https://www.ncbi.nlm.nih.gov/pubmed/33086510
http://dx.doi.org/10.3390/molecules25204787

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