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Deep mutagenesis in the study of COVID-19: a technical overview for the proteomics community
Introduction The spike (S) of SARS coronavirus 2 (SARS-CoV-2) engages angiotensin-converting enzyme 2 (ACE2) on a host cell to trigger viral-cell membrane fusion and infection. The extracellular region of ACE2 can be administered as a soluble decoy to compete for binding sites on the receptor-bindin...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594187/ https://www.ncbi.nlm.nih.gov/pubmed/33084449 http://dx.doi.org/10.1080/14789450.2020.1833721 |