Cargando…

Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling

BACKGROUND: In the central nervous system (CNS), connexin 43 (Cx43) is mainly expressed in astrocytes and regulates astrocytic network homeostasis. Similar to Cx43 overexpression, abnormal excessive opening of Cx43 hemichannels (Cx43Hcs) on reactive astrocytes aggravates the inflammatory response an...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Hailong, Cao, Xiang, Li, Wei, Liu, Pinyi, Zhao, Yuanyuan, Song, Lilong, Chen, Jian, Chen, Beilei, Yu, Wenkui, Xu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594305/
https://www.ncbi.nlm.nih.gov/pubmed/33115476
http://dx.doi.org/10.1186/s12974-020-01978-z