Cargando…

Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling

BACKGROUND: In the central nervous system (CNS), connexin 43 (Cx43) is mainly expressed in astrocytes and regulates astrocytic network homeostasis. Similar to Cx43 overexpression, abnormal excessive opening of Cx43 hemichannels (Cx43Hcs) on reactive astrocytes aggravates the inflammatory response an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Hailong, Cao, Xiang, Li, Wei, Liu, Pinyi, Zhao, Yuanyuan, Song, Lilong, Chen, Jian, Chen, Beilei, Yu, Wenkui, Xu, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594305/ https://www.ncbi.nlm.nih.gov/pubmed/33115476 http://dx.doi.org/10.1186/s12974-020-01978-z

Ejemplares similares

Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway
por: Chen, Yingzhu, et al.
Publicado: (2018)

Connexin43 Hemichannel-Mediated Regulation of Connexin43
por: Li, Kai, et al.
Publicado: (2013)

Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke
por: Freitas-Andrade, Moises, et al.
Publicado: (2019)

The important role of connexin 43 in subarachnoid hemorrhage-induced cerebral vasospasm
por: Yang, Le, et al.
Publicado: (2019)

Role of Connexin 43 in an Inflammatory Model for TMJ Hyperalgesia
por: Ahmed, Fabeeha, et al.
Publicado: (2021)

Connexin 26 and Connexin 43 in Canine Mammary Carcinoma
por: Luu, Savannah, et al.
Publicado: (2019)

Function of Connexin-43 in Macrophages
por: Rodjakovic, Daniel, et al.
Publicado: (2021)

Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling
por: Yu, Hailong, et al.
Publicado: (2020)

Connexin 43 Phosphorylation: Implications in Multiple Diseases
por: Zhang, Meng, et al.
Publicado: (2023)

Connexin 43: An Interface Connecting Neuroinflammation to Depression
por: Jiang, Hong, et al.
Publicado: (2023)

Pathophysiology of SARS-CoV-2 infection in patients with intracerebral hemorrhage
por: Dong, Sisi, et al.
Publicado: (2020)

Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases
por: Li, Wei, et al.
Publicado: (2018)

The Role of Connexin-43 in the Inflammatory Process: A New Potential Therapy to Influence Keratitis
por: Xu, Chu-Yang, et al.
Publicado: (2019)

Internal translation of the connexin 43 transcript
por: Salat-Canela, Clàudia, et al.
Publicado: (2014)

The Role of Connexin 43 in Lung Disease
por: Swartzendruber, Julie A., et al.
Publicado: (2020)

Cytomembrane Trafficking Pathways of Connexin 26, 30, and 43
por: Zong, Yan-Jun, et al.
Publicado: (2023)

The inhibition of indoleamine 2, 3-dioxygenase 1 by connexin 43
por: Lin, Han-Chen, et al.
Publicado: (2017)

Inflammatory Markers and Severity of Intracerebral Hemorrhage
por: Bernstein, Jacob E, et al.
Publicado: (2018)

Gap Junctions and Hemichannels Composed of Connexins and Pannexins Mediate the Secondary Brain Injury Following Intracerebral Hemorrhage
por: Zhang, Yan, et al.
Publicado: (2021)

Anti-inflammatory genes in PBMCs post-spontaneous intracerebral hemorrhage
por: Nguyen, Doan, et al.
Publicado: (2021)

Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
por: Mostafavi, Hossein, et al.
Publicado: (2014)

Connexin 43 impacts on mitochondrial potassium uptake
por: Boengler, Kerstin, et al.
Publicado: (2013)

Connexin43 modulates neutrophil recruitment to the lung
por: Sarieddine, Maya Z Richani, et al.
Publicado: (2009)

The Importance of Connexin 43 in Enamel Development and Mineralization
por: Al-Ansari, Sali, et al.
Publicado: (2018)

Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype
por: Boulay, Anne-Cécile, et al.
Publicado: (2018)

Data on Connexin 43 hemichannels regulation of cellular redox in lens
por: Quan, Yumeng, et al.
Publicado: (2021)

Impact of connexin 43 coupling on survival and migration of multiple myeloma cells
por: Zhang, Yangmin, et al.
Publicado: (2017)

Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes
por: Pei, Haiyun, et al.
Publicado: (2017)

Hippocampal Expression of Connexin36 and Connexin43 during Epileptogenesis in Pilocarpine Model of Epilepsy
por: Motaghi, Sahel, et al.
Publicado: (2017)

Connexin 43-autophagy loop in the podocyte injury of diabetic nephropathy
por: Ji, Jialing, et al.
Publicado: (2019)

The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants
por: Churko, Jared M., et al.
Publicado: (2010)

Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention
por: Zhu, Yi, et al.
Publicado: (2022)

MgIG Attenuates Oxaliplatin-induced Hepatotoxicity through Suppression of Connexin 43 in Hepatic Stellate Cells
por: Cao, Yuzhu, et al.
Publicado: (2023)

Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease
por: Wang, Minghuan, et al.
Publicado: (2019)

Connexin43 in Musculoskeletal System: New Targets for Development and Disease Progression
por: An, Senbo, et al.
Publicado: (2022)

Anti-inflammatory effects of Simvastatin in patients with acute intracerebral hemorrhage in an intensive care unit
por: Zhou, Xiurong, et al.
Publicado: (2017)

Transfected connexin45 alters gap junction permeability in cells expressing endogenous connexin43
Publicado: (1995)

Connexin43 and connexin50 channels exhibit different permeability to the second messenger inositol triphosphate
por: Valiunas, Virginijus, et al.
Publicado: (2020)

Connexin Expression in Pituitary Adenomas and the Effects of Overexpression of Connexin 43 in Pituitary Tumor Cell Lines
por: Nunes, Bruno, et al.
Publicado: (2022)

Exosomal connexin 43 regulates the resistance of glioma cells to temozolomide
por: Yang, Zhang-Jian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_932qrt9nhco1h7mcsu4supc56s