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Ni-Catalyzed Reductive and Merged Photocatalytic Cross-Coupling Reactions toward sp(3)/sp(2)-Functionalized Isoquinolones: Creating Diversity at C-6 and C-7 to Address Bioactive Analogues

[Image: see text] Naturally occurring isoquinolones have gained considerable attention over the years for their bioactive properties. While the late-stage introduction of various functionalities at certain positions, namely, C-3, C-4, and C-8, has been widely documented, the straightforward introduc...

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Detalles Bibliográficos
Autores principales: Dumas, Adrien, Garsi, Jean-Baptiste, Poissonnet, Guillaume, Hanessian, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594327/
https://www.ncbi.nlm.nih.gov/pubmed/33134723
http://dx.doi.org/10.1021/acsomega.0c04181