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Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines

BACKGROUND: Gastric cancer is the fifth most frequently diagnosed cancer and the third leading cause of cancer death worldwide. The molecular mechanisms of action for anti-HER-family drugs in gastric cancer cells are incompletely understood. We compared the molecular effects of trastuzumab and the o...

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Detalles Bibliográficos
Autores principales: Ebert, Karolin, Zwingenberger, Gwen, Barbaria, Elena, Keller, Simone, Heck, Corinna, Arnold, Rouven, Hollerieth, Vanessa, Mattes, Julian, Geffers, Robert, Raimúndez, Elba, Hasenauer, Jan, Luber, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594334/
https://www.ncbi.nlm.nih.gov/pubmed/33115415
http://dx.doi.org/10.1186/s12885-020-07540-7