Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature

BACKGROUND: Aging and mortality of patients on waiting lists for kidney transplantation have increased, as a result of the shortage of organs available all over the world. Living donor grafts represent a significant source to maintain the donor pool, and resorting successfully to allografts with art...

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Autores principales: Nguefouet Momo, Rostand Emmanuel, Donato, Paola, Ugolini, Gabriele, Nacchia, Francesco, Mezzetto, Luca, Veraldi, Gian Franco, Marletta, Stefano, Cavallo, Enrico, Eccher, Albino, Giambanco, Annamaria, Cenzi, Daniela, Boschiero, Luigino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594424/
https://www.ncbi.nlm.nih.gov/pubmed/33115426
http://dx.doi.org/10.1186/s12882-020-02097-w
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author Nguefouet Momo, Rostand Emmanuel
Donato, Paola
Ugolini, Gabriele
Nacchia, Francesco
Mezzetto, Luca
Veraldi, Gian Franco
Marletta, Stefano
Cavallo, Enrico
Eccher, Albino
Giambanco, Annamaria
Cenzi, Daniela
Boschiero, Luigino
author_facet Nguefouet Momo, Rostand Emmanuel
Donato, Paola
Ugolini, Gabriele
Nacchia, Francesco
Mezzetto, Luca
Veraldi, Gian Franco
Marletta, Stefano
Cavallo, Enrico
Eccher, Albino
Giambanco, Annamaria
Cenzi, Daniela
Boschiero, Luigino
author_sort Nguefouet Momo, Rostand Emmanuel
collection PubMed
description BACKGROUND: Aging and mortality of patients on waiting lists for kidney transplantation have increased, as a result of the shortage of organs available all over the world. Living donor grafts represent a significant source to maintain the donor pool, and resorting successfully to allografts with arterial disease has become a necessity. The incidence of renal artery fibromuscular dysplasia (FMD) in potential living renal donors is reported to be 2–6%, and up to 4% of them present concurrent extra-renal involvement. CASE PRESENTATION: We present a case of renal transplantation using a kidney from a living donor with monolateral FMD. Resection of the affected arterial segment and its subsequent replacement with a cryopreserved iliac artery graft from a deceased donor were performed. No intraoperative nor post-operative complications were reported. The allograft function promptly resumed, with satisfying creatinine clearance, and adequate patency of the vascular anastomoses was detected by Doppler ultrasounds. CONCLUSION: Literature lacks clear guidelines on the eligibility of potential living renal donors with asymptomatic FMD. Preliminary assessment of the FMD living donor should always rule out any extra-renal involvement. Whenever possible, resection and reconstruction of the affected arterial segment should be taken into consideration as this condition may progress after implantation.
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spelling pubmed-75944242020-10-30 Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature Nguefouet Momo, Rostand Emmanuel Donato, Paola Ugolini, Gabriele Nacchia, Francesco Mezzetto, Luca Veraldi, Gian Franco Marletta, Stefano Cavallo, Enrico Eccher, Albino Giambanco, Annamaria Cenzi, Daniela Boschiero, Luigino BMC Nephrol Case Report BACKGROUND: Aging and mortality of patients on waiting lists for kidney transplantation have increased, as a result of the shortage of organs available all over the world. Living donor grafts represent a significant source to maintain the donor pool, and resorting successfully to allografts with arterial disease has become a necessity. The incidence of renal artery fibromuscular dysplasia (FMD) in potential living renal donors is reported to be 2–6%, and up to 4% of them present concurrent extra-renal involvement. CASE PRESENTATION: We present a case of renal transplantation using a kidney from a living donor with monolateral FMD. Resection of the affected arterial segment and its subsequent replacement with a cryopreserved iliac artery graft from a deceased donor were performed. No intraoperative nor post-operative complications were reported. The allograft function promptly resumed, with satisfying creatinine clearance, and adequate patency of the vascular anastomoses was detected by Doppler ultrasounds. CONCLUSION: Literature lacks clear guidelines on the eligibility of potential living renal donors with asymptomatic FMD. Preliminary assessment of the FMD living donor should always rule out any extra-renal involvement. Whenever possible, resection and reconstruction of the affected arterial segment should be taken into consideration as this condition may progress after implantation. BioMed Central 2020-10-28 /pmc/articles/PMC7594424/ /pubmed/33115426 http://dx.doi.org/10.1186/s12882-020-02097-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Nguefouet Momo, Rostand Emmanuel
Donato, Paola
Ugolini, Gabriele
Nacchia, Francesco
Mezzetto, Luca
Veraldi, Gian Franco
Marletta, Stefano
Cavallo, Enrico
Eccher, Albino
Giambanco, Annamaria
Cenzi, Daniela
Boschiero, Luigino
Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature
title Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature
title_full Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature
title_fullStr Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature
title_full_unstemmed Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature
title_short Kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature
title_sort kidney transplantation from living donor with monolateral renal artery fibromuscular dysplasia using a cryopreserved iliac graft for arterial reconstruction: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594424/
https://www.ncbi.nlm.nih.gov/pubmed/33115426
http://dx.doi.org/10.1186/s12882-020-02097-w
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