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p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen

The mechanisms by which TP53, the most frequently mutated gene in human cancer, suppresses tumorigenesis remain unclear. p53 modulates various cellular processes, such as apoptosis and proliferation, which has led to distinct cellular mechanisms being proposed for p53-mediated tumor suppression in d...

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Detalles Bibliográficos
Autores principales: Valente, Liz J., Tarangelo, Amy, Li, Albert Mao, Naciri, Marwan, Raj, Nitin, Boutelle, Anthony M., Li, Yang, Mello, Stephano Spano, Bieging-Rolett, Kathryn, DeBerardinis, Ralph J., Ye, Jiangbin, Dixon, Scott J., Attardi, Laura D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594498/
https://www.ncbi.nlm.nih.gov/pubmed/32886745
http://dx.doi.org/10.1083/jcb.201908212