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p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen
The mechanisms by which TP53, the most frequently mutated gene in human cancer, suppresses tumorigenesis remain unclear. p53 modulates various cellular processes, such as apoptosis and proliferation, which has led to distinct cellular mechanisms being proposed for p53-mediated tumor suppression in d...
Autores principales: | Valente, Liz J., Tarangelo, Amy, Li, Albert Mao, Naciri, Marwan, Raj, Nitin, Boutelle, Anthony M., Li, Yang, Mello, Stephano Spano, Bieging-Rolett, Kathryn, DeBerardinis, Ralph J., Ye, Jiangbin, Dixon, Scott J., Attardi, Laura D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594498/ https://www.ncbi.nlm.nih.gov/pubmed/32886745 http://dx.doi.org/10.1083/jcb.201908212 |
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